George is like a big teddy bear. Meredith was his major crush at the beginning of show. He got over that after awhile. George was dating Callie and they had broken up. While his dad was in the hospital he grew close with Callie again. After his dad died, he (spur of the moment) asked Callie to marry him. They got married without telling anyone. They had a fight and George went to talk to Izzie. They got drunk and slept together, but it's going to be their little secret. George O'Malley is played by T.R. Knight.